By Joseph Ragaz,Pierre R. Band,James H. Goldie
By Martine J. Smit,Sergio A. Lira,Rob Leurs
establishing with a basic advent on chemokine functionality and chemokine receptor biology, the second one half covers the recognized implications of those signaling molecules in human ailments, comparable to melanoma, neural problems, and viral an infection, together with AIDS. The 3rd half systematically surveys present drug improvement efforts at concentrating on person chemokine receptors, in addition to different chemokine interplay companions, together with up to date experiences from the pharmaceutical industry.
By Hui Kimko,Stephen B. Duffull
By P. Alexander,J. Gielen,A. C. Sartorelli
The textual content first offers fabrics approximately enzymology, equivalent to review of enzyme platforms all for bioreduction of gear and in redox biking, and reductive position of glutathione within the redox biking of oxidizable medicinal drugs. subsequent, the e-book covers papers on bacterial and parasites an infection, which come with aid by way of the intestine microflora of animals and human and aid of nitroimidazoles in vitro and DNA harm. the remainder articles care for melanoma remedy, akin to hypoxia-mediated nitro-heterocyclic medicines within the radio- and chemotherapy of melanoma, and the organic houses of lowered nitroheterocyclics and attainable underlying biochemical mechanisms.
The textual content can be of significant use to researchers and practitioners of medication, pharmacology, and biochemistry.
By Mickey C. Smith Ph.D.
By Sabyasachi Maiti,Kalyan Kumar Sen
The advances in drug supply platforms over contemporary years have ended in a good number of novel supply platforms with the aptitude to revolutionize the therapy and prevention of ailments. Bio-Targets and Drug supply Approaches is an easy-to-read e-book for college students, researchers and pharmaceutical scientists delivering a finished creation to the foundations of complex drug supply and focusing on their present functions and power destiny developments.
By Lory Mitchell Wingate
Today’s best organisations realize the significance of study and improvement (R&D) to take care of and develop marketplace percentage. If businesses are looking to live on into the long run, they have to speed up their R&D-to-market cycles or locate themselves in the back of the competition.
Project administration for learn and improvement: Guiding Innovation for confident R&D results explains the best way to practice confirmed venture administration tips on how to receive confident results in R&D and innovation initiatives. It addresses the explicit elements businesses needs to contemplate whilst utilizing venture administration to scope, outline, and deal with R&D initiatives. It additionally bargains most sensible practices and case experiences that illustrate real purposes of theory.
This e-book information tips on how to support readers optimize ends up in R&D by utilizing established methods derived from the undertaking administration box and different complementary disciplines. each one bankruptcy contains diagrams, surveys, checklists, and question-answer kinds to steer readers in opting for the place their job falls alongside a venture spectrum and to assist them constitution their very own R&D venture.
The equipment provided during this booklet can simply be utilized to innovation tasks and artistic endeavors. As there are restricted resources of knowledge on find out how to make the most of venture administration method successfully in a majority of these initiatives, this ebook is a perfect source for a person seeking to upload constitution and confirmed the right way to let R&D, innovation, and different artistic activities.
By T. Kumazawa,K. Mizumura,Lawrence Kruger
By Werner Weitschies,Wolfgang Mehnert
Dieses Buch unterstützt das Apothekenteam bei der Beratung über den richtigen Einnahmezeitpunkt. Dazu werden die durch Nahrungsaufnahme veränderten physiologischen Bedingungen im Gastrointestinaltrakt dargestellt, die für die Freisetzung und die anschließende Resorption der Wirkstoffe von entscheidender Bedeutung sind. Zudem beschreiben die Autoren die je nach Nahrungsaufnahme variierende Bioverfügbarkeit von Arzneistoffen. Besonders erklärungsbedürftige Arzneistoffe und Darreichungsformen wie orale Zytostatika werden ausführlich behandelt.
Die Tabelle "Empfehlungen zum Einnahmezeitpunkt" liefert für über 670 Arzneistoffe und ihre jeweiligen Handelspräparate die entsprechenden Einnahmeempfehlungen.
Dr. Werner Weitschies ist Professor für Biopharmazie an der Universität Greifswald und Experte für die Arzneistofffreisetzung aus Darreichungsformen. Dr. Wolfgang Mehnert unterrichtet als akademischer Oberrat Pharmazeutische Technologie an der Freien Universität Berlin.
By Erle S. Robertson